The clash will also serve as the final opportunity for players from both teams to put their hands up for State of Origin selection before squads are announced after round 12.
Brisbane are likely to welcome back Reece Walsh from a knee injury that kept him out of Magic Round, with Walters optimistic Payne Haas will be fit to play after picking up a lower leg injury last weekend.
The Titans are looking to rebound after a four-point loss to the Knights last Saturday.
Veteran halfback Kieran Foran is in the frame to return from a hamstring injury for the Gold Coast, with Jayden Campbell also expected to be in the mix.
Two big inclusions with fullback Reece Walsh (knee) and hooker Billy Walters (wrist) back on deck but centre Kotoni Staggs will miss the match due to a fractured rib.
Selwyn Cobbo returns to the centres after playing fullback last week and Josiah Karapani retains his spot in Staggs’ absence.
Walters’ return sees Tyson Smoothy go back to the bench and Blake Mozer make way.
Payne Haas has been named to play despite suffering a toe injury last week.
Tom Weaver has been named to start at halfback and Chris Randall is again the five-eighth with veteran playmaker Kieran Foran listed among the reserves as he looks to return from a hamstring injury.
Aaron Schoupp’s departure to Manly sees Jojo Fifita shift to centre and Tony Francis come in on the wing for his NRL debut.
With Jaimin Jolliffe sidelined by a pec injury, Josiah Pahulu will start in the front row and Joe Stimson joins the bench.
Fullback Jayden Campbell remains sidelined with a knee injury.
