Birmingham City will start their first season in England’s third tier for 29 years with a home match against Reading, while Wrexham will host Wycombe Wanderers on the Welsh club’s return to League One.
Huddersfield Town and Rotherham United, the two sides relegated from the Championship with Birmingham, will travel to Peterborough United and Exeter City respectively to kick off their campaigns at 17:30 BST on Saturday, 10 August.
League Two title winners Stockport County will host Cambridge United on the opening day, while Mansfield Town, who went up automatically alongside the Hatters and Wrexham, will head to Barnsley for the first game of the new League One season on Friday, 9 August.
Crawley Town, who beat Crewe Alexandra in the League Two play off final to seal promotion in May, will face Blackpool in one of the 11 third-tier games kicking off at 17:30 BST on the first Saturday.
Matches across the three English Football League divisions will be staggered that day, with Championship games kicking off earlier, at 12:30 BST, and League Two games taking the traditional 15:00 BST slot.
All of the opening round of fixtures in all three divisions will be broadcast live on Sky Sports as part of their new £935m five-year deal with the EFL.
The first midweek league fixtures of the campaign follow seven weeks later on Tuesday, 1 October.